New device might mean shorter stays on a ventilator
Getting the healthcare supply chain back on track
Smart glasses for delivering remote care
Louisville Slugger steps up to the plate
Know your city!
May 5, 2020
Device may ease medical problems caused by ventilators
Angus Mclachlan, CEO and co-founder of Liberate Medical
A Louisville company has developed a product that may reduce patient time spent on a ventilator.
Mechanical ventilation has been in the news a lot lately as it has been used increasingly in coronavirus treatment. The issue is that the longer a patient is on a ventilator, the more problems that can be introduced, including a weakening of the breathing muscles and cardiac complications. It’s also costly: For every day a person is dependent on mechanical ventilation, costs increase by $1,500.
Liberate Medical, a medical device company located in Crestwood, has developed a product that shows promise in shortening the time spent on a ventilator. Their VentFree stimulator applies non-invasive electrical stimulation to the abdominal muscles during exhalation in order to prevent abdominal muscle atrophy and reduce ventilation duration in mechanically ventilated patients.
Angus Mclachlan, Liberate Medical’s co-founder and CEO, came to the Louisville from his native Scotland in 2011 in order to work for Apellis Pharmaceuticals. Mclachlan worked on the device hardware and software development side at Apellis, as well as in clinical protocol development, preparing grants and establishing clinical and commercial partnerships. It was during his tenure there that he became aware of the research behind mechanical ventilation.
After developing the VentFree stimulator Liberate Medical performed a double-blind pilot study with a group of 20 participants. The result of the study was that the ICU length of stay and ventilation duration appeared to be shorter compared to the control group. Last October, the company received CE marking for stimulator and ISO 13485 certification (the standard for a Quality Management System for the design and manufacture of medical devices).
The product has received the "CE mark" or certification mark from a European Union regulatory body that allows device makers to sell their products. Liberate Medical is at the beginning of the effort to commercialize the product. The company is starting with a soft launch in a limited number of countries and then will expand throughout the entirety of the EU.
“The process of FDA approval is likely to take about two years, but we have applied for the FDA Emergency Use Authorization. And last year we received the Breakthrough Device Designation from the FDA, which helps with the normal FDA process,” Mclachlan said. The Emergency Use Authorization authority allows the FDA to help strengthen the nation’s public health protections against CBRN (Chemical, biological, radiological and nuclear defense) threats by facilitating the availability and use of MCMs needed during public health emergencies.
Staying in Louisville
Mclachlan decided to launch Liberate Medical in Louisville for several reasons, aside from its increasingly strong health care sector. “I had already made contacts here and they were easy to reach and communicate with. I really like the city and the cost of living here makes it quite attractive. It’s just a great city.”
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TO YOUR HEALTH
Healthcare-supply startup swamped by coronavirus marketplace
If you could time-travel back to 2014, you might create a business that specializes in helping healthcare facilities find the medical supplies they need. That’s what Louisville entrepreneur Kyle Green did, sans the time travel. His company, HANDLE Global, is a healthcare supply chain analytics and solutions platform. That means they use analytics to help healthcare facilities buy beds, stretchers, ventilators, monitors, pumps, gowns, and masks.
And then in 2020, all hell broke loose. With COVID-19 driving demand, hospitals across the country were unable to buy the equipment and supplies they needed, especially with states bidding against each other. For over a month, the company worked around the clock to help clients find personal protective equipment (PPE) and other supplies on the secondary market.
Critically, they also helped hospitals decide what not to buy. “We’ve probably saved health systems and states tens of millions of dollars on items that they should not buy because they were not fully credible sources,” said Green.
Now HANDLE Global is moving beyond its initial mission to create a total fleet management system, helping hospitals understand how they’re using their equipment and tracking data for hospitals so they know what they’ll need when. That is sure to be a valuable approach, once the pandemic passes.
UofL tests smart glasses for telehealth in nursing homes
The smart glasses could be particularly useful for delivering remote care to patients in long-term care facilities (LTCs) during the pandemic. The glasses, worn by an onsite healthcare provider, can connect to the attending physician via Zoom, enabling the doctor to directly interact with the patient in real time.
Toni Ganzel, MD, dean of the UofL School of Medicine, said the glasses are key to the advancement of telemedicine. “The timing had to be right for this technology to become more accepted. It will be a big part of health care moving forward, even after this swell with the COVID-19 pandemic, and it will be exciting to see some of our current medical residents incorporate telemedicine into their future practices.”
Caught in a pickle, Louisville Slugger maker scores with PPE
H&B is selling the masks under its glove brand names, Maskonic and Bionic Gloves. The masks, which are not intended for medical use, are water repellant and their antibacterial effectiveness is good for up to ten washes. “While we’re helping to protect the health of the citizenry, this is also bringing some financial health to our company at a time that it’s very much needed,” said H&B spokesman Rick Redman.
LEARNING IN LOUISVILLE
Leadership Green Room Microlearning
Due to COVID-19, The Leadership Louisville Center had to advance its new strategic plan faster than anticipated. The new normal of virtual access to programming is making it possible for members and guests to attend the free Leadership Green Room Microlearning offerings. Here's the schedule for May:
Tuesday, May 5, 3-4 p.m.– A Conversation with Marshall Goldsmith, Executive Coach & New York Times #1 best-selling author.
Tuesday, May 19, 2-3 p.m. Your Roadmap to Trust, with Justin Patton, Leadership Presence Expert and award-winning author.
Friday, May 29, 9-10 a.m. – Leading with Grace During a Pandemic, with Fiona Campbell, Organizational Psychologist and Executive Coach.
We're going for a PhD
What better place to have a school that teaches about the craft-distillery industry than in the heart of bourbon country? That was Flavorman founder David Dafoe’s thought when he decided to launch Moonshine University, bringing together specialists from every facet of the distilling and spirits industries under one roof to provide technical training, support, and services for start-ups, distilleries, industry professionals, and those looking for careers in the distilling industry.
Dafoe, who formerly worked for Brown-Forman but went out on his own to start Flavorman, recognized the potential for the university when the craft-distilling movement began to take on momentum. He saw that the tremendous surge in demand for distilling permits had no foundation: there was no formalized education catering specifically to these emerging craft enterprises.
Moonshine University opened in the summer of 2012. The premier class is six days and it costs $6,250. Dafoe said, “This course is the first and best of its kind. Attendees receive comprehensive, hands-on learning in all things distilling from the industry’s greatest mentors. Since we started offering it, we’ve filled nearly class and have a waiting list.”
We publish Scrapbook because we believe the best way to envision our future is to have a good understanding of where we've been. We hope you enjoy our fascinating "look back!"
Let's all go to the movies!
While some folks spent the weekend watching first-run movies at the likes of Showcase Cinemas, others frequented smaller, independent neighborhood theaters, like The Vogue and The Uptown.
The 800-seat Vogue Theater, which was located at 3727 Lexington Road, was a center for arthouse films, cult films, foreign films and more--a place where you could go see something that kind of pushed the envelope. Also, it was the place where The Rocky Horror Picture Show was screened continuously for over two decades. It opened on December 22, 1939 and closed in September 1998. It was such a beloved institution that there’s even a Facebook page devoted to it.
Located in the Shuster Building at the intersection of Eastern Parkway and Bardstown Road, the Uptown Theatre was the first theatre to be equipped for showing both silent and sound films. Like the Vogue, it ran second run, B-movies and classic films. It opened in 1928 and continued operations until 1989.
The theatre’s auditorium was demolished for parking space in April of 1994 but its front entrance and lobby area have survived as part of the renovated Schuster Building.
KNOW YOUR CITY!
Have you checked your "Louis-Q" recently?
John Timmons’ ear X-tacy was an institution during its 26 years as an alternative record store. While bands, many local, would come and play on the premises, one was memorable for its turnout on July 4, 2000. Who was the band?
There’s a cave in E.P. “Tom” Sawyer State Park that’s accessible to the public. What’s the cave’s unusual name and what was its purpose previously?
He owned a house at the corner of Frankfort Avenue and William Street in Clifton that, with its wrought-iron enclosed courtyard, was filled with oddball antiques, including a reduced scale replica of the Statue of Liberty bearing Richard Nixon’s face. Who was he?